Haloperidol

  • Name:Haloperidol
  • CAS:52-86-8
  • Purity:99%
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1.What is the Haloperidol ?

White Crystalline Powder

ChEBI: A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.

Haloperidol is a butyrophenone with a long duration of action. It has lile α- adrenoceptor blocking activity and minimal effect on the cardiovascular system. It is an effective antiemetic but has a high incidence of extrapyramidal adverse effects. Haloperidol may be used in the short-term management of the acutely agitated patient (when sinister causes of confusion such as hypoxaemia and sepsis have been excluded) and in the management of delirium in ICU. The duration of action of haloperidol is approximately 24–48h.

2.What is the CAS number for Haloperidol ?

The CAS number of Haloperidol is 52-86-8.

3.What are another words for Haloperidol ?

Synonyms?for?Haloperidol 52-86-8:Butyrophenone,4-[4-(p-chlorophenyl)-4-hydroxypiperidino]-4'-fluoro- (6CI,8CI);4-(4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanone;4-(4-Hydroxy-4'-chloro-4-phenylpiperidino)-4'-fluorobutyrophenone;Aloperidin;Bioperidolo;Brotopon;Dozic;Einalon S;Eukystol;Haldol;Haloperin;Keselan;McN-JR 1625;NSC 615296;Peluces;Serenace;Serenelfi;g-[4-(p-Chlorphenyl)-4-hydroxypiperidino]-p-fluorbutyrophenone;

4.What is Haloperidol (52-86-8) used for?

Haloperidol has been used:in ethanol to serves as an inhibitor of Erg2pto address the mechanism of haloperidol in ferroptosis using hepatocellular carcinoma cells: Hep G2 and Huh-7 cell linesin receptor internalization assayas an antipsychotic drug in Dulbecco′s Modified Eagle medium

InChI:InChI=1/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2/p+1

Relevant articles related to Haloperidol:

Article

Source

An Improved Purification Method for the Rapid Synthesis of High Purity Fluorobutyrophenone Neuroleptics from Nitro and Chloro Precursors Suitable for PET Study

Hashizume, Kazunari,Hashimoto, Naoto,Cork, David G.,Miyake, Yoshihiro

, p. 2295 - 2298 (1994)

Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from: Mycobacterium tuberculosis to overcome kanamycin resistance

Garneau-Tsodikova, Sylvie,Garzan, Atefeh,Green, Keith D.,Holbrook, Selina Y. L.,Hou, Caixia,Krieger, Kyle,Pang, Allan H.,Parish, Tanya,Posey, James E.,Punetha, Ankita,Thamban Chandrika, Nishad,Tsodikov, Oleg V.,Willby, Melisa J.

supporting information, p. 1894 - 1909 (2022/01/12)

Direct C-H Arylation of Aldehydes by Merging Photocatalyzed Hydrogen Atom Transfer with Palladium Catalysis

Chen, Guangying,Cheng, Gui-Juan,Guo, Bin,Li, Xiaobao,Ran, Chongzhao,Wang, Lu,Wang, Ting,Wei, Jun-Jie,Zheng, Caijuan,Zheng, Chao

, p. 7543 - 7551 (2020/08/21)

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