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Factory Sells Best Quality Allopurinol 315-30-0 with steady supply We provide high quality Allopurinol (CAS 315-30-0), at a very affordable prices to our customers.
1.What is the Allopurinol ?
Allopurinol (Zyloprim) is the drug of choice in the treatment of chronic tophaceous gout and is especially useful in patients whose treatment is complicated by renal insufficiency.
Allopurinol does not reduce serum uric acid levels by increasing renal uric acid excretion; instead it lowers plasma urate levels by inhibiting the final steps in uric acid biosynthesis. Uric acid in humans is formed primarily by xanthine oxidase-catalyzed oxidation of hypoxanthine and xanthine to uric acid. Allopurinol (8) and its primary metabolite, alloxanthine (9) [CAS: 2465-59-0], are inhibitors of xanthine oxidase. Inhibition of the last two steps in uric acid biosynthesis by blocking xanthine oxidase reduces the plasma concentration and urinary excretion of uric acid and increases the plasma levels and renal excretion of the more soluble oxypurine precursors. Normally, in humans the urinary purine content is almost solely uric acid; treatment with allopurinol results in the urinary excretion of hypoxanthine, xanthine, and uric acid, each with its independent solubility. Lowering the uric acid concentration in plasma below its limit of solubility facilitates the dissolution of uric acid deposits. The effectiveness of allopurinol in the treatment of gout and hyperuricemia that results from hematogical disorders and antineoplastic therapy has been demonstrated.
2.What is the CAS number for Allopurinol ?
The CAS number of Allopurinol is 315-30-0.
More information of Allopurinol 315-30-0 are:
|
CAS?Number |
315-30-0 |
|
Density |
1.702 g/cm3 |
|
Melting Point |
>300 °C(lit.) |
|
Boiling Point |
423.27 °C at 760 mmHg |
|
Flash Point |
209.787 °C |
|
Vapor Pressure |
0mmHg at 25°C |
|
Refractive Index |
1.8500 (estimate) |
|
HS CODE |
29335990 |
|
PSA |
74.43000 |
|
LogP |
-0.35380 |
|
Pka |
10.2(at 25℃) |
3.What is the molecular formula of Allopurinol ?
The chemical formula of?Allopurinol is C5H4N4O which containing 5 Carbon atoms,4 Hydrogen atoms,4 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight, and the molecular weight of Allopurinol is 136.113
4.What is Allopurinol(315-30-0)used for?
InChI:InChI=1/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)
Relevant articles related to Allopurinol:
|
Article |
Source |
|
- |
Ovcharova et al. , (1973) |
|
INHIBITORS OF Akt ACTIVITY |
- Page/Page column 181, (2010/11/27) |
5.Factory Sells Best Quality Allopurinol 315-30-0 with steady supply
Hebei shuangsheng trading co.,ltd is a quality supplier of Allopurinol. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Allopurinol 315-30-0.
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