Details
Quality products?make an important contribution to long-term revenue and profitability. N-Boc-2-piperidone Good Manufacturer supply High Quality 85908-96-9
1.What is the N-Boc-2-piperidone ?
Intermediate in the preparation of various biological inhibitors.
-
-
675-20-7
piperidin-2-one
-
-
24424-99-5
di-tert -butyl dicarbonate
-
-
85908-96-9
2-oxopiperidine-1-carboxylic acid tert-butyl ester
| Conditions | Yield |
|---|---|
|
piperidin-2-one;
With
n-butyllithium;
In
tetrahydrofuran;
at -78 ℃;
for 0.166667h;
di-tert-butyl dicarbonate;
In
tetrahydrofuran;
at -78 ℃;
for 0.5h;
Further stages.;
|
99%
|
|
piperidin-2-one;
With
n-butyllithium;
In
tetrahydrofuran;
at -78 ℃;
for 0.5h;
Inert atmosphere;
di-tert-butyl dicarbonate;
In
tetrahydrofuran;
at 20 ℃;
for 16h;
Inert atmosphere;
|
98%
|
|
piperidin-2-one;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 0.166667h;
Inert atmosphere;
di-tert-butyl dicarbonate;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 0.75h;
Inert atmosphere;
|
97%
|
|
With
dmap;
In
acetonitrile;
at 20 ℃;
for 1h;
|
96%
|
|
With
dmap; triethylamine;
In
dichloromethane;
at 20 ℃;
for 3h;
|
91%
|
|
With
dmap; triethylamine;
In
dichloromethane;
at 20 ℃;
for 3h;
|
91%
|
|
With
dmap; triethylamine;
In
dichloromethane;
at 20 ℃;
for 3h;
|
91%
|
|
With
dmap; triethylamine;
In
dichloromethane;
at 20 ℃;
for 3h;
|
91%
|
|
With
n-butyllithium;
In
dichloromethane;
at -78 - 20 ℃;
|
90%
|
|
With
dmap;
In
acetonitrile;
at 20 ℃;
for 5h;
|
90%
|
|
With
dmap;
In
acetonitrile;
at 20 ℃;
|
88%
|
|
With
dmap;
In
tetrahydrofuran;
at 20 ℃;
for 18h;
Inert atmosphere;
|
86%
|
|
With
dmap;
In
dichloromethane;
|
85%
|
|
With
dmap; triethylamine;
In
dichloromethane;
at 0 - 20 ℃;
for 48h;
|
85%
|
|
With
dmap; triethylamine;
In
dichloromethane;
at 0 - 20 ℃;
for 48h;
|
85%
|
|
With
dmap; triethylamine;
In
dichloromethane;
at 25 ℃;
for 8h;
|
84%
|
|
With
dmap; N-ethyl-N,N-diisopropylamine;
In
dichloromethane;
at 20 ℃;
Inert atmosphere;
|
84%
|
|
With
dmap;
In
acetonitrile;
at 20 ℃;
for 2h;
|
83%
|
|
With
dmap;
In
acetonitrile;
at 22 ℃;
for 2h;
Reagent/catalyst;
Solvent;
Temperature;
|
82%
|
|
With
triethylamine;
dmap;
In
dichloromethane;
at 20 ℃;
for 32h;
|
81%
|
|
With
dmap; triethylamine;
In
dichloromethane;
at 0 - 20 ℃;
Inert atmosphere;
|
81%
|
|
With
dmap; triethylamine;
In
dichloromethane;
at 0 - 20 ℃;
|
80%
|
|
With
dmap; triethylamine;
In
dichloromethane;
at 25 ℃;
for 8h;
Inert atmosphere;
|
80%
|
|
dmap;
In
acetonitrile;
|
79%
|
|
piperidin-2-one;
With
n-butyllithium;
In
tetrahydrofuran;
at -78 ℃;
for 0.25h;
di-tert-butyl dicarbonate;
In
tetrahydrofuran;
at -78 - 20 ℃;
Further stages.;
|
78%
|
|
With
dmap; triethylamine;
In
acetonitrile;
at 0 - 20 ℃;
for 18h;
|
77%
|
|
With
dmap;
In
acetonitrile;
for 24h;
Ambient temperature;
|
74%
|
|
With
dmap; triethylamine;
In
dichloromethane;
at 20 ℃;
for 12h;
|
74%
|
|
piperidin-2-one;
With
n-butyllithium;
In
tetrahydrofuran;
at -78 ℃;
for 0.25h;
Inert atmosphere;
di-tert-butyl dicarbonate;
In
tetrahydrofuran;
at -78 ℃;
for 0.5h;
Inert atmosphere;
|
72%
|
|
With
dmap; triethylamine;
In
dichloromethane;
at 0 - 20 ℃;
for 12h;
|
68%
|
|
With
dmap; triethylamine;
In
acetonitrile;
at 18 ℃;
for 16h;
Inert atmosphere;
|
67.25%
|
|
With
dmap; triethylamine;
In
dichloromethane;
at 25 ℃;
for 16h;
|
50%
|
|
With
dmap;
In
dichloromethane;
at 20 ℃;
for 24h;
|
48%
|
|
With
n-butyllithium;
Yield given. Multistep reaction;
1.) THF, -78 deg C, 30 min, 2.) 3 h;
|
|
|
With
dmap;
In
acetonitrile;
for 4h;
Ambient temperature;
|
0.90 g
|
|
With
n-butyllithium;
Multistep reaction;
1) THF, -78 deg C, 30 min; 2) THF, -78 deg C, 3 h;
|
|
|
With
dmap;
In
dichloromethane;
|
|
|
With
dmap; triethylamine;
In
hexane; dichloromethane; ethyl acetate;
|
|
|
piperidin-2-one;
With
lithium diisopropyl amide;
In
tetrahydrofuran;
at -70 - -60 ℃;
for 1h;
di-tert-butyl dicarbonate;
In
tetrahydrofuran;
at -70 - 20 ℃;
With
water;
In
tetrahydrofuran; toluene;
for 0.5h;
|
|
|
piperidin-2-one;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at 0 ℃;
for 1h;
Inert atmosphere;
di-tert-butyl dicarbonate;
In
tetrahydrofuran; hexane;
at 0 ℃;
for 2h;
Inert atmosphere;
|
|
|
piperidin-2-one;
With
dmap; triethylamine;
In
acetonitrile;
at 0 ℃;
for 0.166667h;
di-tert-butyl dicarbonate;
In
acetonitrile;
at 20 ℃;
for 2h;
|
|
|
With
dmap;
In
acetonitrile;
at 0 ℃;
for 24h;
|
6.07 g
|
|
With
dmap;
In
acetonitrile;
at 20 ℃;
for 3h;
Inert atmosphere;
|
|
|
With
dmap; triethylamine;
In
dichloromethane;
|
|
|
With
dmap; triethylamine;
In
dichloromethane;
at 20 ℃;
for 3h;
|
|
|
With
dmap; TEA;
In
dichloromethane;
at 0 - 20 ℃;
|
|
|
piperidin-2-one;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at 0 ℃;
for 0.5h;
Inert atmosphere;
di-tert-butyl dicarbonate;
In
tetrahydrofuran; water;
at 0 - 20 ℃;
for 2h;
Inert atmosphere;
|
|
|
With
dmap; triethylamine;
In
dichloromethane;
at 20 ℃;
for 24h;
|
-
-
piperidone monohydrate hydrochloride
-
-
24424-99-5
di-tert -butyl dicarbonate
-
-
85908-96-9
2-oxopiperidine-1-carboxylic acid tert-butyl ester
| Conditions | Yield |
|---|---|
|
With
potassium hydrogensulfate; N-ethyl-N,N-diisopropylamine;
In
methanol;
|
93%
|
2.What is the CAS number for N-Boc-2-piperidone ?
The CAS number of N-Boc-2-piperidone is 85908-96-9.
More information of N-Boc-2-piperidone 85908-96-9 are:
|
CAS?Number |
85908-96-9 |
|
Density |
1.099 g/cm3 |
|
Melting Point |
34-37 °C |
|
Boiling Point |
319.7 °C at 760 mmHg |
|
Flash Point |
147.1 °C |
|
Vapor Pressure |
0.000334mmHg at 25°C |
|
Refractive Index |
1.481 |
|
HS CODE |
29337900 |
|
PSA |
46.61000 |
|
LogP |
1.87190 |
|
Pka |
-2.29±0.20(Predicted) |
3.What are another words for N-Boc-2-piperidone ?
Synonyms?for?N-Boc-2-piperidone 85908-96-9:1,1-Dimethylethyl2-oxopiperidine-1-carboxylate;2-Oxopiperidine-1-carboxylic acid tert-butylester;N-tert-Butoxycarbonyl-2-piperidinone;tert-Butyl2-oxopiperidine-1-carboxylate;
4.What is the molecular formula of N-Boc-2-piperidone?
The chemical formula of ?N-Boc-2-piperidone is?C10H17NO3 which containing 10 Carbon atoms,17 Hydrogen atoms,1 Nitrogen atoms and 3 Oxygen atoms,and the molecular weight of??N-Boc-2-piperidone?is 199.25.
5.What is N-Boc-2-piperidone (85908-96-9) used for?
InChI:InChI=1/C10H17NO3/c1-10(2,3)14-9(13)11-7-5-4-6-8(11)12/h4-7H2,1-3H3
Relevant articles related to N-Boc-2-piperidone:
|
Article |
Source |
|
TMSOTf-mediated approach to 1,3-oxazin-2-one skeleton through one-pot successive reduction-[4 + 2] cyclization process of imides with ynamides |
Zhang, Chen-Chen,Huo, Zhi-Peng,Tang, Mei-Lin,Liang, Yong-Xi,Sun, Xun supporting information, (2021/03/15) |
|
Br?nsted Acid-Catalyzed Aza-Ferrier Reaction of N, O-Allenyl Acetals: Synthesis of β-Amino-α-methylene Aldehydes |
Tayama, Eiji,Ishikawa, Yuki supporting information, p. 9405 - 9414 (2020/08/14) |
6.Buy N-Boc-2-piperidone with the best price .
Hebei shuangsheng trading co.,ltd is a quality supplier of N-Boc-2-piperidone. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on N-Boc-2-piperidone 85908-96-9.
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